Adobe CC 2018 not opening CR2 files

Photoshop is randomly refusing tp open CR2 files any ideas?

Are they all from the same camera? What camera? I’m assuming it is a camera that you’ve been using without issue? When it “refuses” to open, what is the error message?
What version of Adobe Camera Raw (assuming you are trying to open them directly). Windows / Mac?

Guessing how to help is pretty tough without details.

@Ken_Watkins Yep, we need more info.

Please see this topic to get an idea as to what info we might need to help you, Ken.